health care  
 
All about long QT syndrome causes of Long QT syndrome symptoms of long QT syndrome diagnosis of long QT syndrome treatment for long QT syndrome arrhythmias (abnormal heart rhythms) {bundle branch block cardiac arrhythmia atrial fibrillation atrial flutter supraventricular tachycardia sick sinus syndrome ventricular arrhythmias ventricular tachycardia ventricular fibrillation heart block Brugada syndrome long QT syndrome short QT syndrome Wolff-Parkinson-White syndrome (WPW syndrome)}

What causes Long QT syndrome?

Most cases, especially those in young people, are caused by viruses, such as the coxsackievirus, type B. Other causes include bacteria, rickettsiae, parasites, an adverse drug reaction, arsenic or other toxic substances, or other diseases.

The cause of the long QT syndrome is a mutation in a gene that regulates the heart's electrical system. The mutation causes a defect in heart muscle structures called ion channels that predisposes the heart to lapse into a very rapid, ineffectual rhythm called fibrillation. The mutation responsible for the long QT syndrome is inherited as an autosomal dominant, which means that the mutant gene is on a non-sex chromosome and that each child of an affected parent has a 1 in 2 (50%) chance of inheriting it.

Doctors can record the electrical signal produced by the ions on an electrocardiogram (EKG or ECG) machine. The machine makes a tracing of the signal, called a waveform. The different parts of the waveform are represented by the letters P, Q, R, S, and T.

By looking at the waveform, doctors can see the time it takes for the electrical signal to activate and inactivate your heart's lower chambers (the ventricles). This is called the Q-T interval. A problem in one of the ion channels can prolong the Q-T interval. A prolonged Q-T interval can increase your risk for a type of arrhythmia called torsade de pointes. When torsade de pointes occurs, your heart cannot pump enough oxygen-rich blood to the rest of your body, especially your brain. Torsade de pointes can also lead to ventricular fibrillation, a dangerous form of arrhythmia that causes rapid, uncoordinated contractions in the muscle fibers of the ventricles. With ventricular fibrillation, the heart cannot pump oxygen-rich blood to the rest of the body, which can lead to death.

More information on long QT syndrome

What is long QT syndrome? - Long QT syndrome is a heart condition in which there is an abnormally long delay between the electrical excitation and relaxation of the ventricles of the heart.
What causes Long QT syndrome? - The cause of the long QT syndrome is a mutation in a gene that regulates the heart's electrical system. rrhythmias in individuals with LQTS are often associated with exercise or excitement.
What're the symptoms of the long QT syndrome? - The main symptoms of Long QT syndrome are fainting or loss of consciousness. Torsade de pointes can also lead to ventricular fibrillation.
How is the long QT syndrome diagnosed? - The diagnosis of the long QT syndrome can be made by electrocardiogram (ECG) in about 50% of cases. Early diagnosis is essential.
What's the treatments for long QT syndrome? - There are two treatment options in individuals with LQTS: arrhythmia prevention, and arrhythmia termination.
Heart & cardiovascular disorders Mainpage

Topics in heart disease and cardiovascular disorders

Coronary circulation disorders
Myocardium disorders
Heart valve disorders
Arrhythmias (abnormal heart rhythms)
Heart inflammation and infection
Congenital heart disease
Valvular disease (blood vessels disorders)
Procedures done for coronary artery disease
Devices used in cardiology
Diagnostic tests and procedures for heart diseases
Heart transplant
 

Featured articles on heart disease and cardiovascular disorders

Coronary artery disease
Heart attack (myocardial infarction)
Atherosclerosis
Cardiomyopathy
Cardiac arrhythmia
Heart valve replacement
Congestive heart failure
Aortic aneurysm
Atrial fibrillation
Stroke


All information is intended for reference only. Please consult your physician for accurate medical advices and treatment. Copyright 2005, health-cares.net, all rights reserved. Last update: July 18, 2005